{"id":5,"date":"2020-01-13T11:17:52","date_gmt":"2020-01-13T11:17:52","guid":{"rendered":"https:\/\/demosites.io\/web-agency-gb\/?page_id=5"},"modified":"2024-04-15T16:07:22","modified_gmt":"2024-04-15T14:07:22","slug":"15c42-web-agency-gb-home","status":"publish","type":"page","link":"https:\/\/modsim-pharma.com\/","title":{"rendered":"MODSIM Pharma"},"content":{"rendered":"\n
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Optimizing Drug Discovery through Computational Chemistry<\/strong><\/h2>\n\n\n\n
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At MODSIM Pharma, we specialize in Structure-Based Drug Design<\/strong> with our physics-based proprietary methods and molecular simulations to optimize Drug Discovery.<\/p>\n\n\n\n

Born from groundbreaking research at Uppsala University, we integrate advanced algorithms with machine-learning\/AI capabilities to help companies accelerate Hit Identification, Hit-to-Lead, and Lead Optimization. <\/p>\n<\/div>\n<\/div>\n\n\n\n

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About us<\/a><\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n

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Our products<\/h2>\n\n\n\n
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Target Modelling<\/strong><\/h3>\n\n\n\n

One-stop web interface for the 3D-modeling of G Protein-Coupled Receptors (GPCRs) and other membrane proteins<\/p>\n<\/div>\n\n\n\n

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MD simulation<\/strong>s<\/h3>\n\n\n\n

Optimized MD equilibration protocol for structural refinement of membrane proteins in their natural environment<\/p>\n<\/div>\n<\/div>\n\n\n\n

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FEP calculations<\/h3>\n\n\n\n

Automated workflows for high throughput free energy perturbation (FEP) simulations, adapted for ligand series or for protein mutations<\/p>\n<\/div>\n\n\n\n

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Virtual reaction builder<\/h3>\n\n\n\n

Rapidly generate new synthesizable chemical space using a scaffold hopping approach, and enumeration of multicomponent reactions<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Learn more about our products<\/a><\/div>\n<\/div>\n\n\n\n

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What do we offer?<\/h2>\n<\/div>\n<\/div>\n\n\n\n
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A unique platform<\/h3>\n\n\n\n

Physics-based approach to estimate ligand protein binding affinities.<\/p>\n<\/div>\n\n\n\n

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Extensively tested<\/h3>\n\n\n\n

Benchmarked on all major industry standard datasets.<\/p>\n<\/div>\n\n\n\n

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Fast and cost-efficient<\/h3>\n\n\n\n

Our MD engine, Q, works efficiently on modern hardware architecture.<\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n

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Why MODSIM Pharma?<\/strong><\/p>\n\n\n\n

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10x faster<\/strong><\/h3>\n\n\n\n

by shrinking the simulation boundary to focus on specific areas<\/p>\n<\/div>\n\n\n\n

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High accuracy<\/h3>\n\n\n\n

< 1 kcal\/mol, typical of computationally demanding methods<\/p>\n<\/div>\n\n\n\n

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(much) Cheaper<\/h3>\n\n\n\n

at a fraction of the cost as compared to existing alternatives<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Flexible & Adaptive<\/h3>\n\n\n\n

allowing changes in key parameters for a personalized experience<\/p>\n<\/div>\n\n\n\n

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Easy to implement<\/h3>\n\n\n\n

Modular APIs for integration into own software systems, used in the cloud or on PU\/GPU clusters<\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n

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Contact us to learn how we can accelerate your Drug Discovery journey<\/mark><\/h3>\n\n\n\n

contact@modsim-pharma.com<\/span><\/a><\/p>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"

Our products Why MODSIM Pharma?<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"neve_meta_sidebar":"default","neve_meta_container":"default","neve_meta_enable_content_width":"on","neve_meta_content_width":100,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"on","footnotes":""},"class_list":["post-5","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/modsim-pharma.com\/index.php\/wp-json\/wp\/v2\/pages\/5","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/modsim-pharma.com\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/modsim-pharma.com\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/modsim-pharma.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/modsim-pharma.com\/index.php\/wp-json\/wp\/v2\/comments?post=5"}],"version-history":[{"count":48,"href":"https:\/\/modsim-pharma.com\/index.php\/wp-json\/wp\/v2\/pages\/5\/revisions"}],"predecessor-version":[{"id":904,"href":"https:\/\/modsim-pharma.com\/index.php\/wp-json\/wp\/v2\/pages\/5\/revisions\/904"}],"wp:attachment":[{"href":"https:\/\/modsim-pharma.com\/index.php\/wp-json\/wp\/v2\/media?parent=5"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}